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Since ginseng was discovered over 5,000 years ago, it has long been used as a herbal tonic throughout East Asia. Ginseng is a well-known for its multiple health benefits which include recovering energy, improving vitality, relieving stress, maintaining good immunity, etc. However, the benefits of ginseng can only be experienced after prolonged intake, due to the low bioavailability of ginseng active compounds, ginsenosides.
Ginsenosides are bioactive compounds in ginseng that contributes to its pharmacological actions in human body and strengthens immunity. These large molecules must be broken down by intestinal microflora to be absorbed. Nevertheless, factors such as health condition, diet and stress may affect our intestinal microflora, causing different individuals to absorb ginsenosides differently.
Alpha-Wellness™ Red Ginseng ensures that your body readily absorb the maximum benefits of Korean red ginseng bioactive compounds from our proprietary ginseng biotransformation technology. Our Alpha-Wellness™ Red Ginseng is clinically proven to have 115 times higher absorption of powerful ginseng bioactive compound, Compound K, as compared to regular red ginseng*.
Alpha-Wellness™ Red Ginseng manufacturing plant is certified with Good Manufacturing Practices (GMP) by Korea Ministry of Food and Drug Safety.
Fun Facts about Red Ginseng
Do you know that red ginseng is produced from normal raw ginseng (Panax ginseng)? Ordinary white ginseng is produced by air-drying the raw ginseng after peeling off the skin. The red color is attributed to the repetitive steaming and air-drying process (98 – 100oC for 2-3hr) of raw ginseng.
Red ginseng is more pharmacological effective than white ginseng as the steaming-drying process gelatinizes the ginseng starch and increases the content of ginsenosides.
(*Choi, Il-Dong, et al. “Enhanced Absorption Study of Ginsenoside Compound K (20-O-β-(D-Glucopyranosyl)-20 (S)-protopanaxadiol) after Oral Administration of Fermented Red Ginseng Extract (HYFRG™) in Healthy Korean Volunteers and Rats.” Evidence-Based Complementary and Alternative Medicine 2016 (2016).)
In this study, the anti- inflammatory activities of ginsenoside Rb1, which is a main constituent of the root of Panax ginseng (Araliaceae), and of its metabolite compound K were investigated. Compound K potently inhibited the production of substances leading to inflammation (NO and prostaglandin E2) in immune system cells (macrophage). These findings suggest that ginsenoside Rb1 can be transformed to compound K by intestinal bacteria, and compound K may be effective against inflammation.
(Park, Eun-Kyung, et al. “Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264. 7 cells induced by lipopolysaccharide.” Biological and Pharmaceutical Bulletin 28.4 (2005): 652-656)
30 healthy adults were divided into two group: one received 2 g of Alpha-Wellness Red Ginseng while the other received normal red ginseng and their immune cells (IgA and IgG) were analysed. After one week, the increase in IgA and IgG levels by Alpha-Wellness Red Ginseng was higher compared to that by normal red ginseng. These results suggest that Alpha-Wellness Red Ginseng may improve immune-stimulating activities in the human body.
(Kim, Bong-Gwan, et al. “Fermentation of Korean red ginseng by Lactobacillus plantarum M-2 and its immunological activities.” Applied biochemistry and biotechnology 165.5-6 (2011): 1107-1119.)
a. 23 male taxi drivers (43 – 65-year-old) received either red ginseng and placebo before and after their work. Their mental fatigue level was measured. Individuals who consumed red ginseng experienced less mental fatigue after work whereas the placebo group did not experience any effect, indicating that red ginseng helps in relieving work stress and improving cognitive performance.
(Kaneko, Hitoshi, and Kozo Nakanishi. “Proof of the mysterious efficacy of ginseng: basic and clinical trials: clinical effects of medical ginseng, Korean red ginseng: specifically, its anti-stress action for prevention of disease.” Journal of pharmacological sciences 95.2 (2004): 158-162.)
b. Mice were fed with the following test materials for 3 weeks before forced swimming test: 1) Normal diet; 2) Positive control (100mg/kg Resveratrol); 3) 300mg/kg red ginseng (JRG); 4) 300 mg/kg Alpha-Wellness red ginseng (AWRG).
The results showed that AWRG significantly increased total swimming time of mice and delayed the onset of exhaustion. AWRG also significantly suppressed fatigue substance (lactic acid) in the mice’s skeletal muscle.
(Wang, Jia, et al. “Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng CA Meyer.” Journal of ethnopharmacology130.2 (2010): 421-423.)
60 patients with erectile dysfunction were given 1) Placebo & 2) 1000mg Alpha-Wellness Red Ginseng (KRG) capsule, 3 times a day for 12 weeks. Questionnaire were conducted to calculate their International Index of Erectile Function (IIEF-5) score before and after the experiment.
AWRG group showed significant improvement in the IIEF-5 score after 12-week treatment with Korean Red Ginseng, indicating a potential role of it to be an effective alternative phytotherapy for treating male erectile dysfunction.
(De Andrade, Enrico, et al. “Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction.” Asian journal of andrology 9.2 (2007): 241-244.)
5. Skin Protection
Hairless mice were fed with two doses (125mg/kg and 500mg/kg) of Alpha-Wellness red ginseng and exposed to UVB ray 3 times/week for 8 weeks. Mice which consumed Alpha-Wellness red ginseng showed obvious wrinkle reduction effect and improved skin moisture after 8-week consumption as compared to control.
(Source: Korea Yakult Co. Ltd)
Due to overwhelming number of literature, the scientific support illustrated here is non-exhaustive. All scientific support and clinical studies on product safety and efficacy are available for sighting at our office.